Search on:
IDIOTYPE, IMMUNOGLOBULIN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Immunoglobulin Idiotypes
Descriptor
Spanish
:
Idiotipos de Inmunoglobulinas
Descriptor
Portuguese
:
Idiotipos de Imunoglobulinas
Synonyms
English
:
Idiotype, Immunoglobulin
Immunoglobulin Idiotype
Idiotypes, Immunoglobulin
Tree Number:
D12.644.541.500.745
D12.776.124.486.485.680.745
D12.776.124.790.651.680.745
D12.776.377.715.548.680.745
D23.050.550.750
G02.111.570.060.425.580
G12.500.450
Definition
English
:
Unique genetically-controlled determinants present on
ANTIBODIES
whose specificity is limited to a single group of
proteins
(e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the
IMMUNOGLOBULIN VARIABLE REGION
of both immunoglobin polypeptide chains.
Pharmacological Action:
Immunologic Factors
History Note
English
:
79
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
7313
Unique Identifier:
D007130
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS